This article is part of our Showdown/Single Game DFS Breakdown series.
We get our first regular-season NFL game in Las Vegas on Monday night as the Raiders (+5.5 on DraftKings Sportsbook) host the Saints in a game with a 48.5-point total. The Raiders come in off a 34-30 win at Carolina, a game that included a huge performance from second-year running back Josh Jacobs, who rushed for 93 yards and three touchdowns while also catching four of six targets for 46 receiving yards. Meanwhile, the Saints beat the Buccaneers 34-23 in New Orleans thanks, in part, to running back Alvin Kamara, who scored two touchdowns despite racking up only 67 yards from scrimmage. Both players will be very popular in Monday night's matchup, one that has a $500K top prize on DraftKings ($10 per entry) and $200K on FanDuel ($9 per entry).
It's impossible to dive into this slate without recognizing that one of the best players in the NFL, Saints wide receiver Michael Thomas, will not play because of a high-ankle sprain. His absence cannot be under-stated, and it will likely change how the Saints try to move the ball. It should open up opportunities for others, but that doesn't necessarily mean it'll benefit the wide receivers who move up the depth chart.
We're going to start with running backs because the two starters in this game will play major roles for their respective teams. Alvin Kamara ($11,400 DK, $14,000 FD) is the most expensive player on DraftKings and the third-most expensive player on FanDuel,