The Bengals-Steelers game carries one of the highest over/unders for the week, but Cincinnati is historically one of Ben Roethlisberger's toughest opponents.
James Conner has faded from the collective fantasy football consciousness after three disappointing games, but he's in a spot this week recapture some of his Week 1 glory.
With Evan Engram out with an MCL injury, the target count for Sterling Shepard is set to spike upward in a potential shootout setting.
Kareem Hunt somehow has just two targets in the first two weeks, but look for him to regain his standard form at home against the 49ers.
After conquering the West Coast in his 2018 debut, Patrick Mahomes takes the Chiefs to a more hostile Pittsburgh venue in Week 2.
Chris Carson picked up momentum all preseason, but a trap game awaits in Denver. The article also examines NO vs TB and NE vs HOU.