Potential rotation in the Liverpool attack could alter some fantasy lineups, but Mohamed Salah will be a popular option if he starts at home to Stoke City.
Liverpool look set to rest regular starters like Mohamed Salah and Roberto Firmino, which should open up a few key value plays when they host Stoke City at Anfield.
Tottenham are big favorites at home against Brighton on Wednesday, and while Harry Kane is always a hat trick candidate, don't forget about Son Heung-Min.
A win Wednesday against Spartak Moscow will clinch the top spot in Group E for Liverpool, and they will be looking for Mohamed Salah to continue his excellent run.
Mohamed Salah has four goals in his last four matches in all competitions, and he'll look to extend his streak of fine play Saturday at West Ham.
Sunday's two-game slate will make for tricky roster decisions because of no late swap, but Paul Pogba's spot in the starting XI is basically guaranteed.
Sergio Aguero returns after his four-match ban, and Kevin Swanson likes the Argentine as a solid upper-tier option who comes in cheaper than both Diego Costa and Zlatan Ibrahimovic.
With FanDuel introducing English Premier League contests this week, RotoWire's Andrew Laird looks into the key stats to focus on when building lineups.