This article is part of our Sweet 16 Preview series.
The Midwest Region is one of two regions in this year's NCAA Tournament to have its top three seeds advance to the Sweet 16. No. 1 seed Louisville, No. 2 seed Duke and No. 3 seed Michigan State had little trouble advancing, and Friday night's matchup between Duke and Michigan State will pit two of the most successful programs in college basketball over the last quarter century. There is a Cinderella in the region as well, as No. 12 seed Oregon easily dismissed Oklahoma State and Saint Louis in the first two rounds to further confirm the lack of respect the tournament committee gave the Ducks. The headliners in this region are still the coaches, with Rick Pitino, Mike Krzyzewski, Tom Izzo and Dana Altman leading these teams into the Sweet 16.
No. 1 Louisville vs. No. 12 Oregon
Key Matchup: Louisville's Peyton Siva vs. Oregon's Dominic Artis. Siva has not scored at a high level to this point in the tournament, averaging just eight points per game, but he has averaged 6.5 assists per game and has just five turnovers through two games. The diminutive Artis had 13 points in the Ducks' win over Oklahoma State, and his defensive effort helped keep Cowboys guard Marcus Smart in check throughout that game. Don't look for a huge scoring total from either of these guys, but the point guard that